水稻抗病分子育种创新团队

团队简介:水稻抗病分子育种创新团队以稻瘟病、白叶枯病、稻曲病等水稻主要病害为研究对象,围绕新抗源筛选与鉴定、新抗病基因定位与克隆、抗病分子机理解析、抗病分子育种等开展工作,获得重要抗病基因,揭示抗病分子机制,培育抗病优质高产水稻新品种。团队组建10多年来,鉴定筛选出20余份优异抗病水稻资源;定位克隆7个稻瘟病主效抗性基因;揭示了水稻U-box E3泛素连接酶SPL11通过泛素化降解小G蛋白激活酶启动细胞程序化死亡实现抗病性的新机制;通过分子标记辅助育种改良了100余份杂交稻亲本的稻瘟病和白叶枯病抗性,获得数千份抗病水稻新品系;参与育成33个水稻新品种,获得34份植物新品种权和7个国家发明专利;获国家技术发明二等奖1项,省部级科技成果一等奖2项、二等奖3项;承担国家自然科学基金、国家973计划、国家转基因育种重大专项、科技部农业成果转化资金项目、湖南省自然科学基金杰出青年基金等40余个国家级或省部级科研项目;在国内外学术期刊上发表研究论文240余篇。

团队成员:

刘雄伦,教授,1968年3月出生,主要研究方向为水稻稻瘟病抗性基因工程及分子育种。

肖应辉,研究员,1970年9月出生,主要研究方向为水稻杂种优势利用和水稻抗逆高产分子遗传基础研究。

刘金灵,副教授,1983年3月出生,主要研究方向为水稻抗病分子生物学及分子育种。

重要成果:

1.水稻两用核不育系C815S选育及种子生产新技术,2012年国家技术发明二等奖(肖应辉第3)。

2.水稻广谱抗稻瘟病基因的克隆与抗病信号途径解析,2011年湖南省自然科学奖二等奖(刘雄伦第3、肖应辉第5、刘金灵第6)

3.作物耐旱基因克隆鉴定与分子机理研究,2009年湖南省自然科学奖二等奖(刘雄伦第2)

4.Jinling Liu#, Chan Ho Park#, Feng He#, Minoru Nagano, Mo Wang, Maria Bellizzi,Kai Zhang,Xiaoshan Zeng,Wende Liu, Yuese Ning, Yoji Kawano, Guo-Liang Wang*. The RhoGAP SPIN6 directly associates with SPL11 and OsRac1 and negatively regulates programmed cell death and innate immunity in rice. PLOS Pathogens 2015, 11(2): e1004629.

5.Jinling Liu#, Wei Li#, Yuese Ning#, Gautam Shirekar, Xuli Wang, Liangying Dai, Zhilong Wang, Wende Liu and Guo-Liang Wang*. The U-box E3 ligase SPL11/PUB13 is a convergence point of defense and flowering signaling in plants. Plant Physiology 2012, 160:28-37.

6.Jinling Liu#, Xuejun Wang#, Thomas Mitchell, Yajun Hu, Liangying Dai*, and Guo-Liang Wang*. Recent progress and understanding of the molecular mechanisms

of the rice–Magnaporthe oryzae interaction. Molecular Plant Pathology 2010, 11(3):419-427.

7.Nan Jiang#,Zhiqiang Li#,Jun Wu,Yue Wang, Liqun Wu,Suhua Wang, Dan Wang, Ting Wen,Yi Liang,Pingyong Sun,Jinling Liu,Liangying Dai,Zhilong Wang,Chao Wang, Meizhong Luo,Xionglun Liu* and Guo-Liang Wang*.Molecular mapping of the Pi2/9 allelic gene Pi2-2 conferring broad-spectrum resistance to Magnaporthe oryzae in the rice cultivar Jefferson. Rice,2012,5:29.

8.Nan Jiang#, Jun Yan, Yi Liang, Yanlong Shi, Zhizhou He, Yuntian Wu, Qin Zeng, Xionglun Liu* and Junhua Peng*.Resistance Genes and their Interactions with Bacterial Blight/Leaf Streak Pathogens(Xanthomonas oryzae) in Rice (Oryza sativa L.)—an Updated Review. Rice,2020, 13:3

9.Hongmei Huang#, Ling Huang#, Guangping Feng, Suhua Wang, Yue Wang, Jinling Liu,Nan Jiang,Weiting Yan, Lingchao Xu, Pingyong Sun,Zhiqiang Li, Sujun Pan, Xionglun Liu, Yinghui Xiao*, Erming Liu*, Liangying Dai,Guoliang Wang*. Molecular mapping of the new blast resistance genes Pi47 and Pi48 in the durably resistant local rice cultivar Xiangzi 3150. Phytopathology, 2011, 101(5):620-626

10.Qiuhong Chen#, Gai Zeng, Ming Hao, Haoyu Jiang, Yinghui Xiao*. Improvement of rice blast and brown planthopper resistance of PTGMS line C815S in two-line hybrid rice through marker-assisted selection. Mol Breeding, 2020, 40: 21.