何昕

 
职务职称:
讲师
最高学历:
博士研究生
研究领域:
油菜分子生物学
E-mail:
lilindw@163.com
 
工作经历:
2017-06至今,湖南农业大学,农学院,2011南方粮油作物协同创新中心“油菜分子生物学创新团队”引进人才,讲师。主要开展早熟油菜逆境分子生物学研究。
学习经历:
2008-09至2016-12,华中农业大学,植物科学技术学院/作物遗传改良国家重点实验室,作物遗传育种,硕-博士,导师:张献龙教授。
2004-09至2008-06,华中农业大学,植物科学技术学院,植物科学与技术,学士,导师:杨光圣教授。
 
讲授《育种学总论》、《现代农业概论》、《现代农业生物技术》等课程。
 
湖南农业大学硕导,2011南方粮油作物协同创新中心“油菜分子生物学创新团队”骨干,湖南农业大学油菜团队骨干。
主要开展早熟油菜逆境分子生物学研究:搜集自然群体,创建突变体,筛选鉴定优良早熟抗逆甘蓝型油菜种质,利用全基因组关联分析、图位克隆、反向遗传等技术手段挖掘和克隆参与调控甘蓝型油菜早熟抗逆(特别是抗寒抗冻)的基因,揭示其作用分子机理;同时结合基因编辑等生物技术手段,创造出满足“南方稻田作物多熟制”生产重大需求的早熟抗寒且农艺性状优良的油菜种质,为油菜基因组设计育种提供理论基础和基因资源。
先后主持、参与国家自然科学基金、国家重大专项、湖南省教育厅科学研究优秀青年基金等科研项目10余项;在Plant Journal,Plant physiology,Plant Biotechnology Journal,Communications Biology等杂志上发表SCI论文26篇,其中第一作者发表SCI论文9篇。
 
  • 基于CRISPR/Cas9技术靶向突变BnFLCs编码区及其启动子顺式元件E-box创造早熟抗寒甘蓝型油菜的探索研究,主持,31801398,国家自然科学基金青年项目;2019.01.01-2021.12.31。
  • 甘蓝型油菜CaM/CML家族基因鉴定和BnaCML24/38/49功能研究;19B264,湖南省教育厅科学研究优秀青年基金项目,主持,2020.01.01-2021.12.31。
  • BnaCML24和BnaCML49在甘蓝型油菜抗冻性中的功能研究;湖南农业大学作物学科优秀人才基金项目,主持,2019.01.01-2020.12.31。
  • 南方三熟制早熟油菜品种花期耐寒性及其生理生化特性研究;17QN24,湖南农业大学科学基金项目,主持,2017.01.01-2019.12.31。
  • 转基因油菜新品种培育及产业化研究子课题:长江中游转基因油菜新品种培育;SQ2018ZD080068,国家科技重大专项项目,参与,2018.01.01-2020.12.31。
  • 解析油菜滞绿基因BnNYE1启动子光响应顺式元件的变异及其对叶绿素含量和含油量的影响;31801399,国家自然科学基金青年项目,参与,2019.01.01-2021.12.31。
  • 棉花GhCIPK6 的克隆及其调控棉花抗旱的分子机理研究;31371675,国家自然科学基金面上项目,参与,2014.01.01-2017. 12.31。
  • SSN基因家族调控棉花抗黄萎病反应的功能解析;31271772,国家自然科学基金面上项目,参与,2013.01.01-2016. 12.31。
  • 油菜产业技术体系(种质创新岗位);湖南省现代农业产业技术体系岗位专家,参与,2019.01.01-2020.12.31。
  • 甘蓝型油菜Bn.C3VIN3基因的功能验证分析;17QN23,湖南农业大学科学基金项目,参与,2017.01.01-2019.12.31。
 
  • Xin He, Xiangyin Luo, Tianyi Wang, Shiming Liu, Xianlong Zhang, Longfu Zhu, GhHB12 negatively regulates abiotic stress tolerance in Arabidopsis and cotton, Environmental and Experimental Botany, 2020, 176, 104087, https://doi.org/10.1016/j.envexpbot.2020.104087.
  • He Xin, Liao Li, Xie Sai, Yao Min, Xie Pan, Liu Wei, Kang Yu, Huang Luyao, Wang Mei, Qian Lunwen, Liu Zhongsong, Guan Chunyun, Guan Mei*, Hua Wei*. Comprehensive analyses of the annexin (ANN) gene family in Brassica rapa, Brassica oleracea and Brassica napus reveals their roles in stress response. Scientific Reports, 2020, 10(1): 4295.
  • He Xin, Sai Xie, Pan Xie, Min Yao, Wei Liu, Lunwen Qin, Zhongsong Liu, Ming Zheng, Hongfang Liu, Mei Guan, Wei Hua. Genome-wide identification of stress-associated proteins (SAP) with A20/AN1 zinc finger domains associated with abiotic stresses responses in Brassica napus. Environmental and Experimental Botany, 2019, 165:108-119.
  • He Xin, Ni Xianchao, Xie Pan, Liu Wei, Yao Min, Kang Yu, Qin Lunwen and Hua Wei. Comparative Transcriptome Analyses Revealed Conserved and Novel Responses to Cold and Freezing Stress in Brassica napus L. G3: Genes, Genomes, Genetics, 2019, 9(8): 2723-2737.
  • He, X., Wang, T., Xu, Z., Liu, N., Wang, L., Hu, Q., Luo, X., Zhang, X., and Zhu, L. The cotton HD-Zip transcription factor GhHB12 regulates flowering time and plant architecture via the GhmiR157-GhSPL pathway. Communications Biology, 2018, 1: 229.
  • He, X., Wang, T., Zhu, W., Wang, Y., and Zhu, L. GhHB12, a HD-ZIP I Transcription Factor, Negatively Regulates the Cotton Resistance to Verticillium dahliae. International Journal of Molecular Sciences, 2018, 19:3997.
  • He, X., Zhu, L., Wassan, G. M., Wang, Y., Miao, Y., Shaban, M., Hu, H., Sun, H., Zhang, X.*, GhJAZ2 attenuates cotton resistance to biotic stresses via the inhibition of the transcriptional activity of GhbHLH171. Molecular Plant Pathology, 2018, 19(4), 896-908.
  • Hu, H.#, He, X.#, Tu, L., Zhu, L., Zhu, S., Ge, Z., Zhang, X.*, GhJAZ2 negatively regulates cotton fiber initiation by interacting with the R2R3-MYB transcription factor GhMYB25-like. The Plant Journal, 2016, 88(6): 921-935
  • He, X., Zhu, L.*, Xu, L., Guo, W., Zhang, X., GhATAF1, a NAC transcription factor, confers abiotic and biotic stress responses by regulating phytohormonal signaling networks. Plant Cell Reports, 2016, 35(10): 2167-2179.
参与作者论文:
  • M. Yao, M. Guan, Z. Zhang, Q. Zhang, Y. Cui, H. Chen, W. Liu, H.U. Jan, K.P. Voss-Fels, C.R. Werner, X. He, Z. Liu, C. Guan, R.J. Snowdon, W. Hua, L. Qian, GWAS and co-expression network combination uncovers multigenes with close linkage effects on the oleic acid content accumulation in Brassica napus, BMC genomics, 2020, 21:320
  • X. Luo, C. Li, X. He, X. Zhang, L. Zhu, ABA signaling is negatively regulated by GbWRKY1 through JAZ1 and ABI1 to affect salt and drought tolerance, Plant Cell Reports, 2020, 39:181-194
  • Y. Zhou, L. Sun, G.M. Wassan, X. He, M. Shaban, L. Zhang, L. Zhu, X. Zhang, GbSOBIR1 confers Verticillium wilt resistance by phosphorylating the transcriptional factor GbbHLH171 in Gossypium barbadense, Plant biotechnology journal, 2019, 17:152-163.
  • Y. Miao, L. Xu, X. He, L. Zhang, M. Shaban, X. Zhang, L. Zhu, Suppression of tryptophan synthase activates cotton immunity by triggering cell death via promoting SA synthesis, The Plant journal, 2019, 98:329-345.
  • Y. Miao, L. Xu, X. He, L. Zhang, M. Shaban, X. Zhang, L. Zhu, Suppression of tryptophan synthase activates cotton immunity by triggering cell death via promoting SA synthesis, The Plant journal, 2019, 98:329-345.
  • T. Qin, S. Liu, Z. Zhang, L. Sun, X. He, K. Lindsey, L. Zhu, X. Zhang, GhCyP3 improves the resistance of cotton to Verticillium dahliae by inhibiting the E3 ubiquitin ligase activity of GhPUB17, Plant molecular biology, 2019, 99:379-393.
  • W.J. Tang, X. He, L.W. Qian, F. Wang, Z.H. Zhang, C. Sun, L.B. Lin, C.Y. Guan, Comparative Transcriptome Analysis in Oilseed Rape (Brassica napus) Reveals Distinct Gene Expression Details between Nitrate and Ammonium Nutrition, Genes, 2019,10:391.
  • LIU Wei, YAO Ming, KANG Yu, WANG Mei, XIE Pan, HE Xin, LIU Zhong-Song, GUAN Chun-Yun, QIAN Wei, HUA Wei, QIAN Lun-Wen, GWAS and Coexpression Network Combination Uncovers Effect Loci in the Accumulation of Glucosinolates Content in Brassica napus, 农业生物技术学报, 2019, 27:1729-1741.
  • H. Sun, L. Chen, J. Li, M. Hu, A. Ullah, X. He, X. Yang, X. Zhang, The JASMONATE ZIM-Domain Gene Family Mediates JA Signaling and Stress Response in Cotton, Plant and Cell Physiology, 2017, 58:2139-2154.
  • W. Guo, L. Jin, Y. Miao, X. He, Q. Hu, K. Guo, L. Zhu, X. Zhang, An ethylene response-related factor, GbERF1-like, from Gossypium barbadense improves resistance to Verticillium dahliae via activating lignin synthesis, Plant molecular biology, 2016, 91:305-318.
  • Y. Wang, S. Jin, L. Min, X. He, Y. Li, Y. Zhu, Y. Nie, X. Zhang, L. Zhu, The Sophora Alopecuroid H+-PPase Gene SaVP1 Confers Multiple Abiotic Stress Tolerance in Arabidopsis, Plant Molecular Biology Reporter, 2015, 33:923-930.
  • C. Li, X. He, X. Luo, L. Xu, L. Liu, L. Min, L. Jin, L. Zhu, X. Zhang, Cotton WRKY1 Mediates the Plant Defense-to-Development Transition during Infection of Cotton by Verticillium dahliae by Activating JASMONATE ZIM-DOMAIN1 Expression, Plant Physiology, 2014, 166: 2179-2194.
  • L. Xu, W. Zhang, X. He, M. Liu, K. Zhang, M. Shaban, L. Sun, J. Zhu, Y. Luo, D. Yuan, X. Zhang, L. Zhu, Functional characterization of cotton genes responsive to Verticillium dahliae through bioinformatics and reverse genetics strategies, Journal of experimental botany, 2014, 65:6679-6692.
  • L. Long, W. Gao, L. Xu, M. Liu, X. Luo, X. He, X. Yang, X. Zhang, L. Zhu, GbMPK3, a mitogen-activated protein kinase from cotton, enhances drought and oxidative stress tolerance in tobacco, Plant Cell, Tissue and Organ Culture (PCTOC), 2014, 116:153-162.
  • L. Long, W. Gao, L. Xu, M. Liu, X. Luo, X. He, X. Yang, X. Zhang, L. Zhu, GbMPK3, a mitogen-activated protein kinase from cotton, enhances drought and oxidative stress tolerance in tobacco, Plant Cell, Tissue and Organ Culture (PCTOC), 2014, 116:153-162.
  • L. Xu, K.R. Zahid, L. He, W. Zhang, X. He, X. Zhang, X. Yang, L. Zhu, GhCAX3 gene, a novel Ca2+/H+ exchanger from cotton, confers regulation of cold response and ABA induced signal transduction, PloS one, 2013, 8:e66303.
  • L. Xu, L. Jin, L. Long, L. Liu, X. He, W. Gao, L. Zhu, X. Zhang, Overexpression of GbWRKY1 positively regulates the Pi starvation response by alteration of auxin sensitivity in Arabidopsis, Plant Cell Reports, 2012, 31:2177-2188.
  • L.-f. Zhu, X. He, D.-j. Yuan, L. Xu, L. Xu, L.-l. Tu, G.-x. Shen, H. Zhang, X.-l. Zhang, Genome-Wide Identification of Genes Responsive to ABA and Cold/Salt Stresses in Gossypium hirsutum by Data-Mining and Expression Pattern Analysis, Agricultural Sciences in China, 2011, 10:499-508.
 
  • 杨细燕,孙恒,何昕,张献龙. 超表达GhJAZ1基因增强植物抗低温胁迫. 专利申请号:2015105624453